AlphaFold2 and NMR: powerful complements for studying the SARS-CoV-2 Main Protease

Integrative structural biology with solution NMR spectroscopy

Integrating NMR data (and more) with molecular simulations to determine protein structural ensembles

Bio-NMR in the post-GWAS era: from genetic association to pathway elucidation

An allosteric protein switch enables DNA proofreading by High-fidelity Cas9

Using NMR to investigate protein-protein and protein-membrane interactions in Ral signalling pathways

Recombinant Production, Labeling, Purification and Interaction of Death Receptor 5 with Multivalent Peptides

Interaction of the respiratory syncytial virus non-structural protein 1 with the MED25 subunit of the mediator complex

Quantitative description of intrinsically disordered proteins using single-molecule FRET, NMR and SAXS

Structural Investigation of Full-Length Deubiquitinating Enzyme USP14 in Solution

Structural basis of microRNA sponging by HuR

Calculating representative structures of IDP compact conformations based on paramagnetic observables

Structural investigation of OutG, major pseudopilus component from Dickeya dadantii type II secretion system

Interaction of a periplasmic transporter system with the peptidoglycan layer

NMR study of the interaction between ALS related G-quadruplex and nucleolin-derived RG/RGG-rich peptides

hCoV-HKU1 nucleocapsid protein is more specific in dsRNA melting and LLPS than SARS-CoV-2

Context-Dependent Affinities in an Intramolecular Complex of the Signaling Transductor CIN85 rationalize phase separation behaviour

Analysis of sidechain dynamics using slow-relaxing methyl quadruple-quantum coherences

Methodical improvements for studying multi-site exchange in Cadherin-11

Ligand dynamics within the hCAII:SBR complex studied by solution NMR

Characterization of backbone dynamics of ubiquitin-specific protease 7:inhibitor complex using solution NMR

Interaction of AD GENETIC RISK FACTORS: Characterization of PYK2 AND BIN1 protein-protein interaction

Characterization of the conformational space of intrinsically disordered proteins

Unexpected secondary structure propensity for the N-term of RhoGDI 

Visualizing the assembly of a MAPK cell signaling complex

The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a

Coupled Segmental Dynamics of Membranous Cholesterol Captured by 3D Solid-State NMR and MD Simulations

A NMR-based method to quantify membrane partitioning of amphitropic peptides and proteins

Allosteric communication in tryptophan synthase studied by ssNMR

Protein backbone and side-chains motions with 100 kHz MAS NMR

Screening novel mammalian expression systems and isotope labeling schemes for in-cell NMR studies

NMR and biochemical characterization of modification circuits in tRNAs

Structural studies of Sis1 J-domain with the C-terminal region of Hsp70

NMR metabolomics in vitro model of the chronic low-dose exposition to a cocktail of Persistent Organic Pollutants

 Metabolomics of brewer’s malt wort fermentation and in vivo yeast metabolomics by NMR

Structural characterisation of novel natural products from rare actinomycetes Dactylosporangium vinaceum and fulvum using solution NMR, MS, and analysis of their biosynthesis 

Biophysics meets biology to unserstand the mechanism of action of an antiprion Porphyrin

Fragment-Based Lead Discovery by Computational and NMR strategies Aimed to Design SARS-CoV-19 Mpro inhibitors

Repositioning FDA-approved drugs for inhibiting Biliverdin IXβ reductase B as a novel thrombocytopenia therapeutic target

NMR of p47 for drug development

Innovative isotopic labeling approaches for NMR investigation of protein biologics  

Innovative isotopic labeling approaches enabling NMR investigation of monoclonal antibodies at atomic resolution

A fresh look at cross-correlated relaxation: determining and comparing J(0) of complementary spin pairs

Hyperpolarised amino acids using dissolution dynamic nuclear polarization (D-DNP) for kinetic study of the action of L-asparaginase and glutaminase enzymes

Quadrupolar NMR relaxation for ions in aqueous solutions from classical molecular dynamics

NMR characterization of protein-protein interactions involved in PTP modulation and related diseases

Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids

EMMI: An Integrative Approach to Determine Protein Structural Ensembles

ARIAXC Modifying ARIA2 to Use XPLOR-NIH for Structure Calculation

Probing the cell interior by NMR: Protein solubility, stability and protein surface crosstalk with the cellular surroundings

Screening novel mammalian expression systems and isotope labeling schemes for in-cell NMR studies

The unique application of NMR in illuminating the blind spots in structural biology

Interactions! Interactions everywhere!

New tools simplifying access to ultra-high field NMR and enhancing the capabilities for structural biology research

Dynamics in large protein assemblies

Mg²⁺-dependent structural dynamics of a transmembrane channel
by magic-angle spinning NMR

Integrative Structural Biology of Protein Assemblies: Challenges and Opportunities for Magnetic Resonance

NMR metabolomics off the beaten tracks

An NMR-based metabolomic view of the natural history of COVID-19 disease

Systems Biochemistry by NMR

Dissection of CXCL12-HMGB1 heterocomplex reveals that HMGB1 acidic tail contributes to fuzzy intermolecular interactions

Unraveling the structure and dynamics of rJast disintegrin by NMR, insights into the interaction with αvβ3 integrin

The flexible regions of CAF-1 drive tetrasome assembly through their binding to histones and DNA

Structural Analysis of SARS-CoV2 Fusion Peptide in Micelle 

Integrated Tools for MAX family effector prediction, modelling and structure 

CCPN Analysis Structure version 3 as an integrated tool for NMR based structure biology

GltJ protein: Structure & Role in the regulation of the Adventurous motility of Myxococcus xanthus

Weak binding of ATP to the Nerve Growth Factor: a new modulation of neurotrophin signaling?

Role of a glycosaminoglycan-binding motif in the internalization of Engrailed-2 homeoprotein

Evolution of Cadmium versus Copper Binding Selectivity towards extant Metal Selective Helix pomatia Metallothioneins

Structural and functional study of a frog peptide LL-TIL

Structural Characterization of Transiently Populated States of Human HSP90 N-Terminal Domain

Phosphorylation of the DNA-binding protein 'BAF' changes its conformational landscape

Conformational dynamics of the open and closed states of human spindle assembly checkpoint associated protein MAD2

Multivalent interactions of XLF and XRCC4 intrinsically disordered regions underlie liquid-liquid phase separation of NHEJ machinery

Investigation of KIF2C phase separation and its interaction with phosphorylated BRCA2

Incorporation of conformationally biased fluoroprolines into NCBD reveals the role of prolines in the conformational heterogeneity of a molten globule

Cross-correlated relaxation in IDPs - Separating structure and dynamics

Investigations on IDPs by NMR Spectroscopy

Structural determination of NS2B protein of Zika virus and interaction studies with NS3 viral protease

Side Chain Dynamics of the α_1B-Adrenergic Receptor

dGAE (297-391) tau filaments seen by solid-state NMR

Improving selective DNP (SelDNP) for biomolecular applications

Redox regulation of photosynthesis in micro-algae

Structural analysis of pyrene-labelled G-quadruplexes derived from the KIT proto‑oncogene

Curvature and Torsion of Protein Main Chain as Local Order Parameters of Protein conformational ensembles

Structural Analysis of Human Prion Protein using NMR Methodologies Under Cell Mimicking Conditions

NMR metabolomic studies of brain diseases, using the Drosophila model

Monitoring metabolism in an E.coli cell free extract by real-time NMR

Speeding up Screening: Improved matching of reference and control peaks in NMR fragment screening using CcpNmr AnalysisScreen

Characterising the binding and activity of fluorinated Pin1 inhibitors 

An FBDD-NMR approach to target the underdog in the Bcl-2 family, Bfl-1

Determining the Conformational Ensembles of PROTACs in Solution

The roles of highly conserved, non-catalytic residues in class A β-lactamases

Correlation among acid-base, redox and NMR chemical shift data of thiolate-disulfide systems

Low power optimal control pulses improve the performance of multidimensional bio-molecular solution NMR experiments at ultrahigh-field (1.2 GHz) spectrometers

Ultrahigh-Resolution NMR with Water Signal Suppression for a Deeper Understanding of the Action of Antimetabolic Drugs on Diffuse Large B‑Cell Lymphoma

NMR structure calculation with ARIA: recent and future developments

Amyloid fibrils seen by ¹⁹F detected MAS NMR spectroscopy at fast MAS regime

Regulation of the DNA-damage response by phosphorylation clusters in the p53 signaling network

In Situ Study of Poly (ADP-ribosylation) by Solid State NMR

Structure and assembly of PulL and PulM, two components of the Klebsiella oxytoca type II secretion system

NMR experiments and biomolecular simulations: A perfect match?

Disordered, fuzzy and sticky: an NMR insight into the most versatile of respiratory syncytial virus proteins

Context matters - integrating structural disorder in structural biology

Structural Studies of the SARS-Cov2 Nucleoprotein-RNA Complex

Dynamic regulation of protein-RNA and chaperone-client recognition

Aiming Higher - In Energy and Functional Understanding of Proteins

Just flexible linkers?

Protein aggregation and interference with it for treatment and diagnosis studied by NMR  and beyond

How does the promiscuous nucleocapsid protein exert specific actions?

NMR: An essential tool for discovery of HIF-2 inhibitors