XII
th International conference
NMR: a tool for biology
Institut Pasteur, May 2nd-4th 2022
Monday, May 2, 2022
Arrival and registration at the conference center: 205 rue de Vaugirard, 75015 Paris |
08.00 am-09.00 am (GMT+1)
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Welcome address: Prof. Stewart Cole, President of Institut Pasteur On behalf of the organizing committee: Eric Leonardis (Bruker Biospin) and Nadia Izadi-Pruneyre (Institut Pasteur, Paris) |
09.00 am-09.15 am (GMT+1)
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INTEGRATIVE STRUCTURAL BIOLOGY |
09.15 am-10.45 am (GMT+1)
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Chair: Nadia Izadi-Pruneyre, Institut Pasteur, CNRS, France |
1
09.15 am (GMT+1) |
AlphaFold2 and NMR: powerful complements for studying the SARS-CoV-2 Main Protease
Ad Bax Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, United States
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2
09.45 am (GMT+1) |
Integrative structural biology with solution NMR spectroscopy
Sebastian Hiller Biozentrum, University of Basel, Switzerland
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3
10.15 am (GMT+1) |
Integrating NMR data (and more) with molecular simulations to determine protein structural ensembles
Massimiliano Bonomi Institut Pasteur, Structural Bioinformatics Unit, Department of Structural Biology and Chemistry; CNRS UMR 3528, Paris, France
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Coffee break |
10.45 am-11.30 am (GMT+1)
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MOLECULAR INTERACTIONS |
11.30 am-1.00 pm (GMT+1)
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Chair: Bruno Kieffer, IGBMC, France |
4
11.30 am (GMT+1) |
Bio-NMR in the post-GWAS era: from genetic association to pathway elucidation
Isabelle Landrieu CNRS ERL9002 BSI Integrative Structural Biology, Lille, France
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5
12.00 pm (GMT+1) |
An allosteric protein switch enables DNA proofreading by High-fidelity Cas9
Nikolaos Sgourakis University of Pennsylvania, United States
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6
12.30 pm (GMT+1) |
Using NMR to investigate protein-protein and protein-membrane interactions in Ral signalling pathways
Helen Mott University of Cambridge, United Kingdom
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Lunch buffet and poster session (presentation by the authors of posters with an odd number) |
1.00 pm-3.00 pm (GMT+1)
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1
1.00 pm (GMT+1) |
Recombinant Production, Labeling, Purification and Interaction of Death Receptor 5 with Multivalent Peptides
Lua Sobron UMR 5248, CBMN, Pessac, France
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3
1.00 pm (GMT+1) |
Interaction of the respiratory syncytial virus non-structural protein 1 with the MED25 subunit of the mediator complex
Jiawei Dong Institut de Chimie des Substances Naturelles, CNRS UPR2301, Université Paris-Saclay, Gif-sur-Yvette, France
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5
1.00 pm (GMT+1) |
Quantitative description of intrinsically disordered proteins using single-molecule FRET, NMR and SAXS
Samuel Naudi-Fabra Institut de Biologie Structurale, Université Grenoble Alpes-CEA-CNRS, Grenoble, France
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7
1.00 pm (GMT+1) |
Structural Investigation of Full-Length Deubiquitinating Enzyme USP14 in Solution
Johannes Salomonsson Department of Physics, Chemistry and Biology (IFM), Linköping University, Linköping, Sweden
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9
1.00 pm (GMT+1) |
Structural basis of microRNA sponging by HuR
Virginie Bernard Laboratoire SABNP (INSERM U 1204), Université d'Evry-Val-d'Essonne, Evry, France
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11
1.00 pm (GMT+1) |
Calculating representative structures of IDP compact conformations based on paramagnetic observables
Andreas Beier Department of Structural and Computational Biology, University of Vienna, Vienna, Austria
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13
1.00 pm (GMT+1) |
Structural investigation of OutG, major pseudopilus component from Dickeya dadantii type II secretion system
Theis Jacobsen Université de Paris, CNRS UMR3528, Structural Bioinformatics Unit, Institut Pasteur, Paris, France
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15
1.00 pm (GMT+1) |
Interaction of a periplasmic transporter system with the peptidoglycan layer
Maximilian Carl Zinke Institut Pasteur Paris, Paris, France
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17
1.00 pm (GMT+1) |
NMR study of the interaction between ALS related G-quadruplex and nucleolin-derived RG/RGG-rich peptides
Matic Kovačič Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia EN-FIST Centre of Excellence, Ljubljana, Slovenia
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19
1.00 pm (GMT+1) |
hCoV-HKU1 nucleocapsid protein is more specific in dsRNA melting and LLPS than SARS-CoV-2
Gisele Amorim Campus Duque de Caxias, Federal University of Rio de Janeiro, Duque de Caxias, Brazil Rio-NMR Network, Rio De Janeiro, Brazil
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21
1.00 pm (GMT+1) |
Context-Dependent Affinities in an Intramolecular Complex of the Signaling Transductor CIN85 rationalize phase separation behaviour
Daniel Sieme Department for NMR-based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany
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23
1.00 pm (GMT+1) |
Analysis of sidechain dynamics using slow-relaxing methyl quadruple-quantum coherences
Chris Waudby Department of Structural and Molecular Biology, UCL, London, United Kingdom
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25
1.00 pm (GMT+1) |
Methodical improvements for studying multi-site exchange in Cadherin-11
Hans Koss Arthur Palmer lab, Columbia University, New York City, United States
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27
1.00 pm (GMT+1) |
Ligand dynamics within the hCAII:SBR complex studied by solution NMR
Julia Kotschy Department for Chemistry and Chemical Biology, TU Dortmund University, Dortmund, Germany
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29
1.00 pm (GMT+1) |
Characterization of backbone dynamics of ubiquitin-specific protease 7:inhibitor complex using solution NMR
Maya Pandya University of Manchester, Manchester, United Kingdom C4X Discovery, Manchester, United Kingdom
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31
1.00 pm (GMT+1) |
Interaction of AD GENETIC RISK FACTORS: Characterization of PYK2 AND BIN1 protein-protein interaction
Lucy Martin ERL9002 Integrative Structural Biology, CNRS, Lille, France U1167 - RID-AGE - Risk Factors and Molecular Determinants of Aging-Related Diseases, Institut Pasteur de Lille, Lille, France
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33
1.00 pm (GMT+1) |
Characterization of the conformational space of intrinsically disordered proteins
Therese Malliavin Institut Pasteur, Structural Bioinfirmatics Unit, Paris, France
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35
1.00 pm (GMT+1) |
Unexpected secondary structure propensity for the N-term of RhoGDI
Sara Medina Gomez CCB, Physical Chemistry II, TU Dortmund University, Dortmund, Germany
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37
1.00 pm (GMT+1) |
Visualizing the assembly of a MAPK cell signaling complex
Thibault Orand UGA, CEA, CNRS, Institut de Biologie Structurale, Grenoble, France
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39
1.00 pm (GMT+1) |
The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a
Maiia Botova Université Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France
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41
1.00 pm (GMT+1) |
Coupled Segmental Dynamics of Membranous Cholesterol Captured by 3D Solid-State NMR and MD Simulations
Taras Pogorelov Chemistry, University of Illinois at Urbana-Champaign, Urbana, United States
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43
1.00 pm (GMT+1) |
A NMR-based method to quantify membrane partitioning of amphitropic peptides and proteins
Mirko Sadi Institut Pasteur, Paris 13, France
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45
1.00 pm (GMT+1) |
Allosteric communication in tryptophan synthase studied by ssNMR
Hanna Kavaleuskaya Dept. of Physical Chemistry, Technical University of Dortmund, Dortmund, Germany
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47
1.00 pm (GMT+1) |
Protein backbone and side-chains motions with 100 kHz MAS NMR
Adrienn Rancz CRMN Lyon, CNRS, Villeurbanne, France
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49
1.00 pm (GMT+1) |
Screening novel mammalian expression systems and isotope labeling schemes for in-cell NMR studies
Hélène Chérot CEA- I2BC, Gif Sur Yvette, France Universite Paris Saclay, Orsay, France
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51
1.00 pm (GMT+1) |
NMR and biochemical characterization of modification circuits in tRNAs
Marcel Joseph Yared IBPC, UMR8261, CNRS, Paris, France
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53
1.00 pm (GMT+1) |
Structural studies of Sis1 J-domain with the C-terminal region of Hsp70
Carolina Matos Institute of Chemistry, University of Campinas Unicamp, Campinas, Brazil
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55
1.00 pm (GMT+1) |
NMR metabolomics in vitro model of the chronic low-dose exposition to a cocktail of Persistent Organic Pollutants
Lucas-Torres Covadonga LCBPT, UMR 8601 CNRS, Université de Paris, Paris, France
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57
1.00 pm (GMT+1) |
Metabolomics of brewer’s malt wort fermentation and in vivo yeast metabolomics by NMR
Marcel Menezes Lyra Da Cunha Campus UFRJ - Duque de Caxias, Núcleo Multidisciplinar de Pesquisa UFRJ – Xerém em Biologia. Universidade Federal do Rio de Janeiro, Duque De Caxias, Brazil
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59
1.00 pm (GMT+1) |
Structural characterisation of novel natural products from rare actinomycetes Dactylosporangium vinaceum and fulvum using solution NMR, MS, and analysis of their biosynthesis
Xavier Trivelli Institut Michel-Eugène Chevreul-FR2638, Univ. Lille, CNRS, INRAE, Centrale Lille, Univ. Artois, Villeneuve D'ascq, France
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61
1.00 pm (GMT+1) |
Biophysics meets biology to unserstand the mechanism of action of an antiprion Porphyrin
Chiara Zucchelli Biomolecular NMR Unit, Ospedale San Raffaele IRCCS, Milano, Italy
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63
1.00 pm (GMT+1) |
Fragment-Based Lead Discovery by Computational and NMR strategies Aimed to Design SARS-CoV-19 Mpro inhibitors
Mattia Sturlese Dept. Pharmaceutical and Pharmacological Sciences, Drug Discovery by NMR Lab, University of Padova, Padova, Italy
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65
1.00 pm (GMT+1) |
Repositioning FDA-approved drugs for inhibiting Biliverdin IXβ reductase B as a novel thrombocytopenia therapeutic target
Myeongkyu Kim Department of NMR Based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany
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67
1.00 pm (GMT+1) |
NMR of p47 for drug development
Nathalie Masson-Lancelot Institut de recherches Servier, Croissy sur Seine, France
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69
1.00 pm (GMT+1) |
Innovative isotopic labeling approaches for NMR investigation of protein biologics
Elodie Crublet NMR-Bio, Grenoble, France
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71
1.00 pm (GMT+1) |
Innovative isotopic labeling approaches enabling NMR investigation of monoclonal antibodies at atomic resolution
Arthur Giraud NMRteam, Institut de Biologie Structurale, Grenoble, France Structural Biologics & Biophysics team, Sanofi, Vitry, France
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73
1.00 pm (GMT+1) |
A fresh look at cross-correlated relaxation: determining and comparing J(0) of complementary spin pairs
Irene Ceccolini Max Perutz Laboratories, Department of Structural and Computational Biology, University of Vienna, Vienna, Austria
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75
1.00 pm (GMT+1) |
Hyperpolarised amino acids using dissolution dynamic nuclear polarization (D-DNP) for kinetic study of the action of L-asparaginase and glutaminase enzymes
Karen Dos Santos Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR CNRS 8601, Université Paris Cité, Paris, France
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77
1.00 pm (GMT+1) |
Quadrupolar NMR relaxation for ions in aqueous solutions from classical molecular dynamics
Iurii Chubak PHENIX UMR 8234, Sorbonne University, CNRS, Paris, France
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79
1.00 pm (GMT+1) |
NMR characterization of protein-protein interactions involved in PTP modulation and related diseases
Simone Fabbian Department of Chemical Sciences, University of Padova, Padova, I-35121, Italy
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81
1.00 pm (GMT+1) |
Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids
Icaro Caruso Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Rio De Janeiro, Brazil Multiuser Center for Biomolecular Innovation (CMIB), Department of Physics, São Paulo State University (UNESP), São José Do Rio Preto, Brazil Rio BioNMR Network, Rio De Janeiro, Brazil
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83
1.00 pm (GMT+1) |
EMMI: An Integrative Approach to Determine Protein Structural Ensembles
Samuel Hoff Institut Pasteur, Paris, France
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85
1.00 pm (GMT+1) |
ARIAXC Modifying ARIA2 to Use XPLOR-NIH for Structure Calculation
Gary Thompson Wellcome Trust NMR Facility, School of Biosciences, University of Kent, Canterbury, United Kingdom
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IN CELL NMR |
3.00 pm-4.00 pm (GMT+1)
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Chair: Françoise Ochsenbein, CEA/CNRS, France |
7
3.00 pm (GMT+1) |
Probing the cell interior by NMR: Protein solubility, stability and protein surface crosstalk with the cellular surroundings
Jens Danielsson Stockholm University, Sweden
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8
3.30 pm (GMT+1) |
Screening novel mammalian expression systems and isotope labeling schemes for in-cell NMR studies
François-Xavier Theillet CNRS, Gif-sur-Yvette, France
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Coffee break |
4.00 pm-4.45 pm (GMT+1)
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PUSHING THE FRONTIERS OF NMR |
4.45 pm-6.15 pm (GMT+1)
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Chair: Dominique Marion, Institut de Biologie Structurale, France |
9
4.45 pm (GMT+1) |
The unique application of NMR in illuminating the blind spots in structural biology
Haribabu Arthanari Harvard University, United States
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10
5.15 pm (GMT+1) |
Interactions! Interactions everywhere!
Fabien Ferrage Laboratoire des Biomolécules, LBM, Département de chimie, École normale supérieure, PSL University, Sorbonne Université, CNRS, Paris, France
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11
5.45 pm (GMT+1) |
New tools simplifying access to ultra-high field NMR and enhancing the capabilities for structural biology research
Rainer Kuemmerle Bruker Biospin, Switzerland
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Conference cocktail |
6.15 pm-8.30 pm (GMT+1)
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Tuesday, May 3, 2022
SOLID-STATE NMR FOR LARGE COMPLEXES |
09.15 am-10.45 am (GMT+1)
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Chair: Benjamin Bardiaux, Institut Pasteur, CNRS, France |
12
09.15 am (GMT+1) |
Dynamics in large protein assemblies
Paul Schanda IST Austria, Austria
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13
09.45 am (GMT+1) |
Mg2+-dependent structural dynamics of a transmembrane channel
by magic-angle spinning NMR
Guido Pintacuda Centre de RMN à Très Hauts Champs de Lyon, (CNRS / Ecole Normale Supérieure de Lyon / Claude Bernard Université Lyon 1), Villeurbanne, France
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14
10.15 am (GMT+1) |
Integrative Structural Biology of Protein Assemblies: Challenges and Opportunities for Magnetic Resonance
Tatyana Polenova Department of Chemistry and Biochemistry, University of Delaware, Newark, United States
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Coffee break |
10.45 am-11.30 am (GMT+1)
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METABOLOMICS |
11.30 am-1.00 pm (GMT+1)
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Chair: Giovanna Musco, San Raffaele Hospital, Italy |
15
11.30 am (GMT+1) |
NMR metabolomics off the beaten tracks
Patrick Giraudeau Nantes Université, CNRS, CEISAM, UMR 6230, Nantes, France
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16
12.00 pm (GMT+1) |
An NMR-based metabolomic view of the natural history of COVID-19 disease
Oscar Millet CICbioGUNE, Spain
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17
12.30 pm (GMT+1) |
Systems Biochemistry by NMR
Guy Lippens Université de Toulouse, France
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Lunch buffet and poster session (presentation by the authors of posters with an even number) |
1.00 pm-3.00 pm (GMT+1)
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2
1.00 pm (GMT+1) |
Dissection of CXCL12-HMGB1 heterocomplex reveals that HMGB1 acidic tail contributes to fuzzy intermolecular interactions
Malisa Mantonico University San Raffaele (UniSR), Milano, Italy Biomolecular NMR Unit, Hospital San Raffaele (HSR), Milano, Italy
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4
1.00 pm (GMT+1) |
Unraveling the structure and dynamics of rJast disintegrin by NMR, insights into the interaction with αvβ3 integrin
Ariana Vasconcelos Institute of Medical Biochemistry, Center for Structural Biology and Bioimaging (CENABIO), National Center of Nuclear Magnetic Resonance (CNRMN), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
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6
1.00 pm (GMT+1) |
The flexible regions of CAF-1 drive tetrasome assembly through their binding to histones and DNA
Françoise Ochsenbein Joliot, I2BC, CEA/CNRS, Gif sur Yvette, France
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8
1.00 pm (GMT+1) |
Structural Analysis of SARS-CoV2 Fusion Peptide in Micelle
Medine Ayhan Chemistry, University of Illinois at Chicago, Chicago, United States
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10
1.00 pm (GMT+1) |
Integrated Tools for MAX family effector prediction, modelling and structure
Mounia Lahfa CBS, Université de Montpellier, Montpellier, France
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12
1.00 pm (GMT+1) |
CCPN Analysis Structure version 3 as an integrated tool for NMR based structure biology
Eliza Ploskon-Arthur Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, United Kingdom
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14
1.00 pm (GMT+1) |
GltJ protein: Structure & Role in the regulation of the Adventurous motility of Myxococcus xanthus
Bouchra Attia LISM UMR7255, CNRS IMM, Marseille, France
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16
1.00 pm (GMT+1) |
Weak binding of ATP to the Nerve Growth Factor: a new modulation of neurotrophin signaling?
Francesca Paoletti National Institute of Chemistry, Ljubljana, Slovenia
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18
1.00 pm (GMT+1) |
Role of a glycosaminoglycan-binding motif in the internalization of Engrailed-2 homeoprotein
Yadira Hervis Laboratoire des Biomolécules, LBM, Sorbonne University, Paris, France
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20
1.00 pm (GMT+1) |
Evolution of Cadmium versus Copper Binding Selectivity towards extant Metal Selective Helix pomatia Metallothioneins
Renato Valsecchi Chemistry, Chemical Biology/Structure & Analysis, Zerbe, University of Zurich, Zurich, Switzerland
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22
1.00 pm (GMT+1) |
Structural and functional study of a frog peptide LL-TIL
Mihir Rami Molecular Biophysics, Prof. Siddhartha P Sarma's Laboratory, Indian Institute of Science, Bengaluru, India
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24
1.00 pm (GMT+1) |
Structural Characterization of Transiently Populated States of Human HSP90 N-Terminal Domain
Elisa Rioual Institut de Biologie structurale, CEA/CNRS/UGA, Grenoble, France
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26
1.00 pm (GMT+1) |
Phosphorylation of the DNA-binding protein 'BAF' changes its conformational landscape
Agathe Marcelot Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Saclay, France
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28
1.00 pm (GMT+1) |
Conformational dynamics of the open and closed states of human spindle assembly checkpoint associated protein MAD2
Laura Kukuk Fakultät für Chemie und chemische Biologie, TU Dortmund, Dortmund, Germany
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30
1.00 pm (GMT+1) |
Multivalent interactions of XLF and XRCC4 intrinsically disordered regions underlie liquid-liquid phase separation of NHEJ machinery
Duc-Duy Vu Département Chimie, LBM, UMR 7203, École Normale Supérieure, PSL University, Paris, France
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32
1.00 pm (GMT+1) |
Investigation of KIF2C phase separation and its interaction with phosphorylated BRCA2
Anastasiia Skobelkina Institut de Biologie Intégrative de la Cellule (I2BC), CEA, CNRS, Uni Paris-Sud, Uni Paris-Saclay, CEA, Gif-Sur-Yvette, France
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34
1.00 pm (GMT+1) |
Incorporation of conformationally biased fluoroprolines into NCBD reveals the role of prolines in the conformational heterogeneity of a molten globule
Abir Ben Bouzayene integrative structural biology, IGBMC, Strasbourg, France Laboratoire de Chimie des Protéines, ESBS, Illkirch, France
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36
1.00 pm (GMT+1) |
Cross-correlated relaxation in IDPs - Separating structure and dynamics
Clemens Kauffmann Department of Structural and Computational Biology, University of Vienna, Vienna, Austria
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38
1.00 pm (GMT+1) |
Investigations on IDPs by NMR Spectroscopy
Theresa Höfurthner Department for Structural and Computational Biology, Group Konrat, University of Vienna, Max Perutz Laboratories, Vienna, Austria
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40
1.00 pm (GMT+1) |
Structural determination of NS2B protein of Zika virus and interaction studies with NS3 viral protease
Beatriz Rosa Penna Medical Biochemistry Institute, Center for Structural Biology and Bioimaging (CENABIO), National Center of Nuclear Magnetic Resonance (CNRMN), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
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42
1.00 pm (GMT+1) |
Side Chain Dynamics of the α1B-Adrenergic Receptor
Christian Baumann Department of Chemistry, University of Zurich, Zurich, Switzerland
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44
1.00 pm (GMT+1) |
dGAE (297-391) tau filaments seen by solid-state NMR
Kristine Kitoka Latvian Institute of Organic Synthesis, Riga, Latvia
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46
1.00 pm (GMT+1) |
Improving selective DNP (SelDNP) for biomolecular applications
Ons Dakhlaoui IRIG/MEM/RM/DNP, CEA de Grenoble, Grenoble, France CERMAV, CNRS, Grenoble, France
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48
1.00 pm (GMT+1) |
Redox regulation of photosynthesis in micro-algae
Helene Launay BIP, UMR 7281, CNRS, Marseille Cedex 9, France
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50
1.00 pm (GMT+1) |
Structural analysis of pyrene-labelled G-quadruplexes derived from the KIT proto‑oncogene
Kateřina Peterková Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia Masaryk University, Faculty of Science, National Centre for Biomolecular Research, Brno, Czech Republic
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52
1.00 pm (GMT+1) |
Curvature and Torsion of Protein Main Chain as Local Order Parameters of Protein conformational ensembles
Patrick Senet CNRS UMR 6303 Laboratoire ICB, Université de Bourgogne Franche-Comté, Dijon Cedex, France
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54
1.00 pm (GMT+1) |
Structural Analysis of Human Prion Protein using NMR Methodologies Under Cell Mimicking Conditions
Manoj Madheswaran Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Caserta, Italy
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56
1.00 pm (GMT+1) |
NMR metabolomic studies of brain diseases, using the Drosophila model
Céline Landon Centre molecular Biophysics, CNRS, Orleans Cédex 02, France
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58
1.00 pm (GMT+1) |
Monitoring metabolism in an E.coli cell free extract by real-time NMR
Pauline Rouan TBI - INSA, Toulouse, France
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60
1.00 pm (GMT+1) |
Speeding up Screening: Improved matching of reference and control peaks in NMR fragment screening using CcpNmr AnalysisScreen
Victoria Higman Department of Molecular and Cell Biology, University of Leicester, Leicester, United Kingdom
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62
1.00 pm (GMT+1) |
Characterising the binding and activity of fluorinated Pin1 inhibitors
Stephanie Davidson Laboratoire des Biomolécules (UMR:7203), Sorbonne Université, Paris, France
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64
1.00 pm (GMT+1) |
An FBDD-NMR approach to target the underdog in the Bcl-2 family, Bfl-1
Annagiulia Favaro Department of Pharmaceutical and Pharmacological Sciences, Drug Discovery by NMR Lab., University of Padova, Padova, Italy
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66
1.00 pm (GMT+1) |
Determining the Conformational Ensembles of PROTACs in Solution
Julian Holzinger Computational Biology and Biomolecular NMR Spectroscopy, Max Perutz Laboratories, Vienna, Austria
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68
1.00 pm (GMT+1) |
The roles of highly conserved, non-catalytic residues in class A β-lactamases
Marcellus Ubbink Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands
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70
1.00 pm (GMT+1) |
Correlation among acid-base, redox and NMR chemical shift data of thiolate-disulfide systems
Juliana Ferreira De Santana Pharmaceutical Chemistry, Semmelweis University, Budapest, Hungary
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72
1.00 pm (GMT+1) |
Low power optimal control pulses improve the performance of multidimensional bio-molecular solution NMR experiments at ultrahigh-field (1.2 GHz) spectrometers
David Joseph Dept. of NMR-based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany
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74
1.00 pm (GMT+1) |
Ultrahigh-Resolution NMR with Water Signal Suppression for a Deeper Understanding of the Action of Antimetabolic Drugs on Diffuse Large B‑Cell Lymphoma
Xi Chen Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, F-75006 Paris, France, Université Paris Cité, Paris 6e Arrondissement, France
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76
1.00 pm (GMT+1) |
NMR structure calculation with ARIA: recent and future developments
Nathalie Duclert-Savatier Institut Pasteur, Université Paris Cité, CNRS UMR3528, Structural Bioinformatics Unit, Paris, France
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78
1.00 pm (GMT+1) |
Amyloid fibrils seen by 19F detected MAS NMR spectroscopy at fast MAS regime
Alons Lends Latvian institute of organic synthesis, Riga, Latvia Institut de Chimie et de Biologie des Membranes et des Nanoobjets, Institut Européen de Chimie et Biologie, CNRS UMR 5248, Université de Bordeaux, Pessac, France
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80
1.00 pm (GMT+1) |
Regulation of the DNA-damage response by phosphorylation clusters in the p53 signaling network
Yingyue Luo CNRS-I2bc, Bures Sur Yvette, France Univ. Paris-Saclay, France
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82
1.00 pm (GMT+1) |
In Situ Study of Poly (ADP-ribosylation) by Solid State NMR
Adrian Murgoci Yusuf Hamied Department of Chemistry, Duer group, University of Cambridge, Cambridge, United Kingdom
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84
1.00 pm (GMT+1) |
Structure and assembly of PulL and PulM, two components of the Klebsiella oxytoca type II secretion system
Régine Dazzoni Université Paris Cité, CNRS UMR3528, Structural Bioinformatics Unit, F-75015, Institut Pasteur, Paris, France
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DYNAMIC AND DISORDERED SYSTEMS I |
3.00 pm-4.15 pm (GMT+1)
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Chair: Paul Robustelli, Dartmouth College, United States |
18
3.00 pm (GMT+1) |
NMR experiments and biomolecular simulations: A perfect match?
Kresten Lindorff-Larsen Structural Biology and NMR Laboratory, Linderstrøm-Lang Centre for Protein Science, Univ. of Copenhagen, Denmark
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19
3.30 pm (GMT+1) |
Disordered, fuzzy and sticky: an NMR insight into the most versatile of respiratory syncytial virus proteins
Christina Sizun Institut de Chimie des Substances Naturelles, CNRS, Université Paris Saclay, Gif-Sur-Yvette, France
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20
4.00 pm (GMT+1) |
Context matters - integrating structural disorder in structural biology
Birthe Kragelund University of Copenhagen, Denmark
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Coffee break |
4.30 pm-5.15 pm (GMT+1)
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RNA-PROTEIN COMPLEXES |
5.15 pm-6.15 pm (GMT+1)
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Chair: Muriel Delepierre, Institut Pasteur, CNRS, France |
21
5.15 pm (GMT+1) |
Structural Studies of the SARS-Cov2 Nucleoprotein-RNA Complex
Elisar Barbar Oregon State University, United States
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22
5.45 pm (GMT+1) |
Dynamic regulation of protein-RNA and chaperone-client recognition
Michael Sattler Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany Bavarian NMR Center, Department of Chemistry, Technical University of Munich, Garching, Germany
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Wednesday, May 4, 2022
DYNAMIC AND DISORDERED SYSTEMS II |
09.00 am-10.00 am (GMT+1)
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Chair: Iñaki Guijarro, Institut Pasteur, France |
23
09.00 am (GMT+1) |
Aiming Higher - In Energy and Functional Understanding of Proteins
Dorothee Kern Brandeis University, United States
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24
09.30 am (GMT+1) |
Just flexible linkers?
Roberta Pierattelli Magnetic Resonance Center (CERM) and Department of Chemistry “Ugo Schiff”, CERM-University of Florence, Italy
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Coffee break |
10.00 am-10.45 am (GMT+1)
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DRUG DISCOVERY AND DIAGNOSIS |
10.45 am-12.15 pm (GMT+1)
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Chair: Michael Nilges, Institut Pasteur, France |
25
10.45 am (GMT+1) |
Protein aggregation and interference with it for treatment and diagnosis studied by NMR and beyond
Christian Griesinger NMR-based Structural Biology, Max-Planck-Institute for Multidisciplinary Sciences, Göttingen, Germany
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26
11.15 am (GMT+1) |
How does the promiscuous nucleocapsid protein exert specific actions?
Fabio Almeida University Federal Rio De Janeiro, Brazil
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27
11.45 am (GMT+1) |
NMR: An essential tool for discovery of HIF-2 inhibitors
Kevin Gardner Director, Structural Biology Initiative, CUNY Advanced Science Research Center, United States
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Closing remarks: On behalf of the organizing commmitte: Prof. Michael Nilges, Institut Pasteur, Paris |
12.15 pm-12.30 pm (GMT+1)
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CCPN Satellite workshop (only for registered attendees) |
2.00 pm-6.00 pm (GMT+1)
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