Programme
XIIth International conference
NMR: a tool for biology
Institut Pasteur, May 2nd-4th 2022

 
Monday, May 2, 2022
Arrival and registration at the conference center: 205 rue de Vaugirard, 75015 Paris
08.00 am-09.00 am (GMT+1)
Welcome address:
Prof. Stewart Cole, President of Institut Pasteur
On behalf of the organizing committee: Eric Leonardis (Bruker Biospin) and Nadia Izadi-Pruneyre (Institut Pasteur, Paris)
09.00 am-09.15 am (GMT+1)
INTEGRATIVE STRUCTURAL BIOLOGY
09.15 am-10.45 am (GMT+1)
Chair: Nadia Izadi-Pruneyre, Institut Pasteur, CNRS, France
1
09.15 am (GMT+1)

AlphaFold2 and NMR: powerful complements for studying the SARS-CoV-2 Main Protease

Ad Bax
Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, United States
2
09.45 am (GMT+1)

Integrative structural biology with solution NMR spectroscopy

Sebastian Hiller
Biozentrum, University of Basel, Switzerland
3
10.15 am (GMT+1)

Integrating NMR data (and more) with molecular simulations to determine protein structural ensembles

Massimiliano Bonomi
Institut Pasteur, Structural Bioinformatics Unit, Department of Structural Biology and Chemistry; CNRS UMR 3528, Paris, France
Coffee break
10.45 am-11.30 am (GMT+1)
MOLECULAR INTERACTIONS
11.30 am-1.00 pm (GMT+1)
Chair: Bruno Kieffer, IGBMC, France
4
11.30 am (GMT+1)

Bio-NMR in the post-GWAS era: from genetic association to pathway elucidation

Isabelle Landrieu
CNRS ERL9002 BSI Integrative Structural Biology, Lille, France
5
12.00 pm (GMT+1)

An allosteric protein switch enables DNA proofreading by High-fidelity Cas9

Nikolaos Sgourakis
University of Pennsylvania, United States
6
12.30 pm (GMT+1)

Using NMR to investigate protein-protein and protein-membrane interactions in Ral signalling pathways

Helen Mott
University of Cambridge, United Kingdom
Lunch buffet and poster session (presentation by the authors of posters with an odd number)
1.00 pm-3.00 pm (GMT+1)
1
1.00 pm (GMT+1)

Recombinant Production, Labeling, Purification and Interaction of Death Receptor 5 with Multivalent Peptides

Lua Sobron
UMR 5248, CBMN, Pessac, France
3
1.00 pm (GMT+1)

Interaction of the respiratory syncytial virus non-structural protein 1 with the MED25 subunit of the mediator complex

Jiawei Dong
Institut de Chimie des Substances Naturelles, CNRS UPR2301, Université Paris-Saclay, Gif-sur-Yvette, France
5
1.00 pm (GMT+1)

Quantitative description of intrinsically disordered proteins using single-molecule FRET, NMR and SAXS

Samuel Naudi-Fabra
Institut de Biologie Structurale, Université Grenoble Alpes-CEA-CNRS, Grenoble, France
7
1.00 pm (GMT+1)

Structural Investigation of Full-Length Deubiquitinating Enzyme USP14 in Solution

Johannes Salomonsson
Department of Physics, Chemistry and Biology (IFM), Linköping University, Linköping, Sweden
9
1.00 pm (GMT+1)

Structural basis of microRNA sponging by HuR

Virginie Bernard
Laboratoire SABNP (INSERM U 1204), Université d'Evry-Val-d'Essonne, Evry, France
11
1.00 pm (GMT+1)

Calculating representative structures of IDP compact conformations based on paramagnetic observables

Andreas Beier
Department of Structural and Computational Biology, University of Vienna, Vienna, Austria
13
1.00 pm (GMT+1)

Structural investigation of OutG, major pseudopilus component from Dickeya dadantii type II secretion system

Theis Jacobsen
Université de Paris, CNRS UMR3528, Structural Bioinformatics Unit, Institut Pasteur, Paris, France
15
1.00 pm (GMT+1)

Interaction of a periplasmic transporter system with the peptidoglycan layer

Maximilian Carl Zinke
Institut Pasteur Paris, Paris, France
17
1.00 pm (GMT+1)

NMR study of the interaction between ALS related G-quadruplex and nucleolin-derived RG/RGG-rich peptides

Matic Kovačič
Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia EN-FIST Centre of Excellence, Ljubljana, Slovenia
19
1.00 pm (GMT+1)

hCoV-HKU1 nucleocapsid protein is more specific in dsRNA melting and LLPS than SARS-CoV-2

Gisele Amorim
Campus Duque de Caxias, Federal University of Rio de Janeiro, Duque de Caxias, Brazil Rio-NMR Network, Rio De Janeiro, Brazil
21
1.00 pm (GMT+1)

Context-Dependent Affinities in an Intramolecular Complex of the Signaling Transductor CIN85 rationalize phase separation behaviour

Daniel Sieme
Department for NMR-based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany
23
1.00 pm (GMT+1)

Analysis of sidechain dynamics using slow-relaxing methyl quadruple-quantum coherences

Chris Waudby
Department of Structural and Molecular Biology, UCL, London, United Kingdom
25
1.00 pm (GMT+1)

Methodical improvements for studying multi-site exchange in Cadherin-11

Hans Koss
Arthur Palmer lab, Columbia University, New York City, United States
27
1.00 pm (GMT+1)

Ligand dynamics within the hCAII:SBR complex studied by solution NMR

Julia Kotschy
Department for Chemistry and Chemical Biology, TU Dortmund University, Dortmund, Germany
29
1.00 pm (GMT+1)

Characterization of backbone dynamics of ubiquitin-specific protease 7:inhibitor complex using solution NMR

Maya Pandya
University of Manchester, Manchester, United Kingdom C4X Discovery, Manchester, United Kingdom
31
1.00 pm (GMT+1)

Interaction of AD GENETIC RISK FACTORS: Characterization of PYK2 AND BIN1 protein-protein interaction

Lucy Martin
ERL9002 Integrative Structural Biology, CNRS, Lille, France U1167 - RID-AGE - Risk Factors and Molecular Determinants of Aging-Related Diseases, Institut Pasteur de Lille, Lille, France
33
1.00 pm (GMT+1)

Characterization of the conformational space of intrinsically disordered proteins

Therese Malliavin
Institut Pasteur, Structural Bioinfirmatics Unit, Paris, France
35
1.00 pm (GMT+1)

Unexpected secondary structure propensity for the N-term of RhoGDI 

Sara Medina Gomez
CCB, Physical Chemistry II, TU Dortmund University, Dortmund, Germany
37
1.00 pm (GMT+1)

Visualizing the assembly of a MAPK cell signaling complex

Thibault Orand
UGA, CEA, CNRS, Institut de Biologie Structurale, Grenoble, France
39
1.00 pm (GMT+1)

The intrinsically disordered SARS-CoV-2 nucleoprotein in dynamic complex with its viral partner nsp3a

Maiia Botova
Université Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France
41
1.00 pm (GMT+1)

Coupled Segmental Dynamics of Membranous Cholesterol Captured by 3D Solid-State NMR and MD Simulations

Taras Pogorelov
Chemistry, University of Illinois at Urbana-Champaign, Urbana, United States
43
1.00 pm (GMT+1)

A NMR-based method to quantify membrane partitioning of amphitropic peptides and proteins

Mirko Sadi
Institut Pasteur, Paris 13, France
45
1.00 pm (GMT+1)

Allosteric communication in tryptophan synthase studied by ssNMR

Hanna Kavaleuskaya
Dept. of Physical Chemistry, Technical University of Dortmund, Dortmund, Germany
47
1.00 pm (GMT+1)

Protein backbone and side-chains motions with 100 kHz MAS NMR

Adrienn Rancz
CRMN Lyon, CNRS, Villeurbanne, France
49
1.00 pm (GMT+1)

Screening novel mammalian expression systems and isotope labeling schemes for in-cell NMR studies

Hélène Chérot
CEA- I2BC, Gif Sur Yvette, France Universite Paris Saclay, Orsay, France
51
1.00 pm (GMT+1)

NMR and biochemical characterization of modification circuits in tRNAs

Marcel Joseph Yared
IBPC, UMR8261, CNRS, Paris, France
53
1.00 pm (GMT+1)

Structural studies of Sis1 J-domain with the C-terminal region of Hsp70

Carolina Matos
Institute of Chemistry, University of Campinas Unicamp, Campinas, Brazil
55
1.00 pm (GMT+1)

NMR metabolomics in vitro model of the chronic low-dose exposition to a cocktail of Persistent Organic Pollutants

Lucas-Torres Covadonga
LCBPT, UMR 8601 CNRS, Université de Paris, Paris, France
57
1.00 pm (GMT+1)

 Metabolomics of brewer’s malt wort fermentation and in vivo yeast metabolomics by NMR

Marcel Menezes Lyra Da Cunha
Campus UFRJ - Duque de Caxias, Núcleo Multidisciplinar de Pesquisa UFRJ – Xerém em Biologia. Universidade Federal do Rio de Janeiro, Duque De Caxias, Brazil
59
1.00 pm (GMT+1)

Structural characterisation of novel natural products from rare actinomycetes Dactylosporangium vinaceum and fulvum using solution NMR, MS, and analysis of their biosynthesis 

Xavier Trivelli
Institut Michel-Eugène Chevreul-FR2638, Univ. Lille, CNRS, INRAE, Centrale Lille, Univ. Artois, Villeneuve D'ascq, France
61
1.00 pm (GMT+1)

Biophysics meets biology to unserstand the mechanism of action of an antiprion Porphyrin

Chiara Zucchelli
Biomolecular NMR Unit, Ospedale San Raffaele IRCCS, Milano, Italy
63
1.00 pm (GMT+1)

Fragment-Based Lead Discovery by Computational and NMR strategies Aimed to Design SARS-CoV-19 Mpro inhibitors

Mattia Sturlese
Dept. Pharmaceutical and Pharmacological Sciences, Drug Discovery by NMR Lab, University of Padova, Padova, Italy
65
1.00 pm (GMT+1)

Repositioning FDA-approved drugs for inhibiting Biliverdin IXβ reductase B as a novel thrombocytopenia therapeutic target

Myeongkyu Kim
Department of NMR Based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany
67
1.00 pm (GMT+1)

NMR of p47 for drug development

Nathalie Masson-Lancelot
Institut de recherches Servier, Croissy sur Seine, France
69
1.00 pm (GMT+1)

Innovative isotopic labeling approaches for NMR investigation of protein biologics  

Elodie Crublet
NMR-Bio, Grenoble, France
71
1.00 pm (GMT+1)

Innovative isotopic labeling approaches enabling NMR investigation of monoclonal antibodies at atomic resolution

Arthur Giraud
NMRteam, Institut de Biologie Structurale, Grenoble, France Structural Biologics & Biophysics team, Sanofi, Vitry, France
73
1.00 pm (GMT+1)

A fresh look at cross-correlated relaxation: determining and comparing J(0) of complementary spin pairs

Irene Ceccolini
Max Perutz Laboratories, Department of Structural and Computational Biology, University of Vienna, Vienna, Austria
75
1.00 pm (GMT+1)

Hyperpolarised amino acids using dissolution dynamic nuclear polarization (D-DNP) for kinetic study of the action of L-asparaginase and glutaminase enzymes

Karen Dos Santos
Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR CNRS 8601, Université Paris Cité, Paris, France
77
1.00 pm (GMT+1)

Quadrupolar NMR relaxation for ions in aqueous solutions from classical molecular dynamics

Iurii Chubak
PHENIX UMR 8234, Sorbonne University, CNRS, Paris, France
79
1.00 pm (GMT+1)

NMR characterization of protein-protein interactions involved in PTP modulation and related diseases

Simone Fabbian
Department of Chemical Sciences, University of Padova, Padova, I-35121, Italy
81
1.00 pm (GMT+1)

Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids

Icaro Caruso
Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Rio De Janeiro, Brazil Multiuser Center for Biomolecular Innovation (CMIB), Department of Physics, São Paulo State University (UNESP), São José Do Rio Preto, Brazil Rio BioNMR Network, Rio De Janeiro, Brazil
83
1.00 pm (GMT+1)

EMMI: An Integrative Approach to Determine Protein Structural Ensembles

Samuel Hoff
Institut Pasteur, Paris, France
85
1.00 pm (GMT+1)

ARIAXC Modifying ARIA2 to Use XPLOR-NIH for Structure Calculation

Gary Thompson
Wellcome Trust NMR Facility, School of Biosciences, University of Kent, Canterbury, United Kingdom
IN CELL NMR
3.00 pm-4.00 pm (GMT+1)
Chair: Françoise Ochsenbein, CEA/CNRS, France
7
3.00 pm (GMT+1)

Probing the cell interior by NMR: Protein solubility, stability and protein surface crosstalk with the cellular surroundings

Jens Danielsson
Stockholm University, Sweden
8
3.30 pm (GMT+1)

Screening novel mammalian expression systems and isotope labeling schemes for in-cell NMR studies

François-Xavier Theillet
CNRS, Gif-sur-Yvette, France
Coffee break
4.00 pm-4.45 pm (GMT+1)
PUSHING THE FRONTIERS OF NMR
4.45 pm-6.15 pm (GMT+1)
Chair: Dominique Marion, Institut de Biologie Structurale, France
9
4.45 pm (GMT+1)

The unique application of NMR in illuminating the blind spots in structural biology

Haribabu Arthanari
Harvard University, United States
10
5.15 pm (GMT+1)

Interactions! Interactions everywhere!

Fabien Ferrage
Laboratoire des Biomolécules, LBM, Département de chimie, École normale supérieure, PSL University, Sorbonne Université, CNRS, Paris, France
11
5.45 pm (GMT+1)

New tools simplifying access to ultra-high field NMR and enhancing the capabilities for structural biology research

Rainer Kuemmerle
Bruker Biospin, Switzerland
Conference cocktail
6.15 pm-8.30 pm (GMT+1)
Tuesday, May 3, 2022
SOLID-STATE NMR FOR LARGE COMPLEXES
09.15 am-10.45 am (GMT+1)
Chair: Benjamin Bardiaux, Institut Pasteur, CNRS, France
12
09.15 am (GMT+1)

Dynamics in large protein assemblies

Paul Schanda
IST Austria, Austria
13
09.45 am (GMT+1)

Mg2+-dependent structural dynamics of a transmembrane channel
by magic-angle spinning NMR

Guido Pintacuda
Centre de RMN à Très Hauts Champs de Lyon, (CNRS / Ecole Normale Supérieure de Lyon / Claude Bernard Université Lyon 1), Villeurbanne, France
14
10.15 am (GMT+1)

Integrative Structural Biology of Protein Assemblies: Challenges and Opportunities for Magnetic Resonance

Tatyana Polenova
Department of Chemistry and Biochemistry, University of Delaware, Newark, United States
Coffee break
10.45 am-11.30 am (GMT+1)
METABOLOMICS
11.30 am-1.00 pm (GMT+1)
Chair: Giovanna Musco, San Raffaele Hospital, Italy
15
11.30 am (GMT+1)

NMR metabolomics off the beaten tracks

Patrick Giraudeau
Nantes Université, CNRS, CEISAM, UMR 6230, Nantes, France
16
12.00 pm (GMT+1)

An NMR-based metabolomic view of the natural history of COVID-19 disease

Oscar Millet
CICbioGUNE, Spain
17
12.30 pm (GMT+1)

Systems Biochemistry by NMR

Guy Lippens
Université de Toulouse, France
Lunch buffet and poster session (presentation by the authors of posters with an even number)
1.00 pm-3.00 pm (GMT+1)
2
1.00 pm (GMT+1)

Dissection of CXCL12-HMGB1 heterocomplex reveals that HMGB1 acidic tail contributes to fuzzy intermolecular interactions

Malisa Mantonico
University San Raffaele (UniSR), Milano, Italy Biomolecular NMR Unit, Hospital San Raffaele (HSR), Milano, Italy
4
1.00 pm (GMT+1)

Unraveling the structure and dynamics of rJast disintegrin by NMR, insights into the interaction with αvβ3 integrin

Ariana Vasconcelos
Institute of Medical Biochemistry, Center for Structural Biology and Bioimaging (CENABIO), National Center of Nuclear Magnetic Resonance (CNRMN), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
6
1.00 pm (GMT+1)

The flexible regions of CAF-1 drive tetrasome assembly through their binding to histones and DNA

Françoise Ochsenbein
Joliot, I2BC, CEA/CNRS, Gif sur Yvette, France
8
1.00 pm (GMT+1)

Structural Analysis of SARS-CoV2 Fusion Peptide in Micelle 

Medine Ayhan
Chemistry, University of Illinois at Chicago, Chicago, United States
10
1.00 pm (GMT+1)

Integrated Tools for MAX family effector prediction, modelling and structure 

Mounia Lahfa
CBS, Université de Montpellier, Montpellier, France
12
1.00 pm (GMT+1)

CCPN Analysis Structure version 3 as an integrated tool for NMR based structure biology

Eliza Ploskon-Arthur
Leicester Institute of Structural and Chemical Biology, University of Leicester, Leicester, United Kingdom
14
1.00 pm (GMT+1)

GltJ protein: Structure & Role in the regulation of the Adventurous motility of Myxococcus xanthus

Bouchra Attia
LISM UMR7255, CNRS IMM, Marseille, France
16
1.00 pm (GMT+1)

Weak binding of ATP to the Nerve Growth Factor: a new modulation of neurotrophin signaling?

Francesca Paoletti
National Institute of Chemistry, Ljubljana, Slovenia
18
1.00 pm (GMT+1)

Role of a glycosaminoglycan-binding motif in the internalization of Engrailed-2 homeoprotein

Yadira Hervis
Laboratoire des Biomolécules, LBM, Sorbonne University, Paris, France
20
1.00 pm (GMT+1)

Evolution of Cadmium versus Copper Binding Selectivity towards extant Metal Selective Helix pomatia Metallothioneins

Renato Valsecchi
Chemistry, Chemical Biology/Structure & Analysis, Zerbe, University of Zurich, Zurich, Switzerland
22
1.00 pm (GMT+1)

Structural and functional study of a frog peptide LL-TIL

Mihir Rami
Molecular Biophysics, Prof. Siddhartha P Sarma's Laboratory, Indian Institute of Science, Bengaluru, India
24
1.00 pm (GMT+1)

Structural Characterization of Transiently Populated States of Human HSP90 N-Terminal Domain

Elisa Rioual
Institut de Biologie structurale, CEA/CNRS/UGA, Grenoble, France
26
1.00 pm (GMT+1)

Phosphorylation of the DNA-binding protein 'BAF' changes its conformational landscape

Agathe Marcelot
Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Saclay, Saclay, France
28
1.00 pm (GMT+1)

Conformational dynamics of the open and closed states of human spindle assembly checkpoint associated protein MAD2

Laura Kukuk
Fakultät für Chemie und chemische Biologie, TU Dortmund, Dortmund, Germany
30
1.00 pm (GMT+1)

Multivalent interactions of XLF and XRCC4 intrinsically disordered regions underlie liquid-liquid phase separation of NHEJ machinery

Duc-Duy Vu
Département Chimie, LBM, UMR 7203, École Normale Supérieure, PSL University, Paris, France
32
1.00 pm (GMT+1)

Investigation of KIF2C phase separation and its interaction with phosphorylated BRCA2

Anastasiia Skobelkina
Institut de Biologie Intégrative de la Cellule (I2BC), CEA, CNRS, Uni Paris-Sud, Uni Paris-Saclay, CEA, Gif-Sur-Yvette, France
34
1.00 pm (GMT+1)

Incorporation of conformationally biased fluoroprolines into NCBD reveals the role of prolines in the conformational heterogeneity of a molten globule

Abir Ben Bouzayene
integrative structural biology, IGBMC, Strasbourg, France Laboratoire de Chimie des Protéines, ESBS, Illkirch, France
36
1.00 pm (GMT+1)

Cross-correlated relaxation in IDPs - Separating structure and dynamics

Clemens Kauffmann
Department of Structural and Computational Biology, University of Vienna, Vienna, Austria
38
1.00 pm (GMT+1)

Investigations on IDPs by NMR Spectroscopy

Theresa Höfurthner
Department for Structural and Computational Biology, Group Konrat, University of Vienna, Max Perutz Laboratories, Vienna, Austria
40
1.00 pm (GMT+1)

Structural determination of NS2B protein of Zika virus and interaction studies with NS3 viral protease

Beatriz Rosa Penna
Medical Biochemistry Institute, Center for Structural Biology and Bioimaging (CENABIO), National Center of Nuclear Magnetic Resonance (CNRMN), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
42
1.00 pm (GMT+1)

Side Chain Dynamics of the α1B-Adrenergic Receptor

Christian Baumann
Department of Chemistry, University of Zurich, Zurich, Switzerland
44
1.00 pm (GMT+1)

dGAE (297-391) tau filaments seen by solid-state NMR

Kristine Kitoka
Latvian Institute of Organic Synthesis, Riga, Latvia
46
1.00 pm (GMT+1)

Improving selective DNP (SelDNP) for biomolecular applications

Ons Dakhlaoui
IRIG/MEM/RM/DNP, CEA de Grenoble, Grenoble, France CERMAV, CNRS, Grenoble, France
48
1.00 pm (GMT+1)

Redox regulation of photosynthesis in micro-algae

Helene Launay
BIP, UMR 7281, CNRS, Marseille Cedex 9, France
50
1.00 pm (GMT+1)

Structural analysis of pyrene-labelled G-quadruplexes derived from the KIT proto‑oncogene

Kateřina Peterková
Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia Masaryk University, Faculty of Science, National Centre for Biomolecular Research, Brno, Czech Republic
52
1.00 pm (GMT+1)

Curvature and Torsion of Protein Main Chain as Local Order Parameters of Protein conformational ensembles

Patrick Senet
CNRS UMR 6303 Laboratoire ICB, Université de Bourgogne Franche-Comté, Dijon Cedex, France
54
1.00 pm (GMT+1)

Structural Analysis of Human Prion Protein using NMR Methodologies Under Cell Mimicking Conditions

Manoj Madheswaran
Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Caserta, Italy
56
1.00 pm (GMT+1)

NMR metabolomic studies of brain diseases, using the Drosophila model

Céline Landon
Centre molecular Biophysics, CNRS, Orleans Cédex 02, France
58
1.00 pm (GMT+1)

Monitoring metabolism in an E.coli cell free extract by real-time NMR

Pauline Rouan
TBI - INSA, Toulouse, France
60
1.00 pm (GMT+1)

Speeding up Screening: Improved matching of reference and control peaks in NMR fragment screening using CcpNmr AnalysisScreen

Victoria Higman
Department of Molecular and Cell Biology, University of Leicester, Leicester, United Kingdom
62
1.00 pm (GMT+1)

Characterising the binding and activity of fluorinated Pin1 inhibitors 

Stephanie Davidson
Laboratoire des Biomolécules (UMR:7203), Sorbonne Université, Paris, France
64
1.00 pm (GMT+1)

An FBDD-NMR approach to target the underdog in the Bcl-2 family, Bfl-1

Annagiulia Favaro
Department of Pharmaceutical and Pharmacological Sciences, Drug Discovery by NMR Lab., University of Padova, Padova, Italy
66
1.00 pm (GMT+1)

Determining the Conformational Ensembles of PROTACs in Solution

Julian Holzinger
Computational Biology and Biomolecular NMR Spectroscopy, Max Perutz Laboratories, Vienna, Austria
68
1.00 pm (GMT+1)

The roles of highly conserved, non-catalytic residues in class A β-lactamases

Marcellus Ubbink
Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands
70
1.00 pm (GMT+1)

Correlation among acid-base, redox and NMR chemical shift data of thiolate-disulfide systems

Juliana Ferreira De Santana
Pharmaceutical Chemistry, Semmelweis University, Budapest, Hungary
72
1.00 pm (GMT+1)

Low power optimal control pulses improve the performance of multidimensional bio-molecular solution NMR experiments at ultrahigh-field (1.2 GHz) spectrometers

David Joseph
Dept. of NMR-based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Goettingen, Germany
74
1.00 pm (GMT+1)

Ultrahigh-Resolution NMR with Water Signal Suppression for a Deeper Understanding of the Action of Antimetabolic Drugs on Diffuse Large B‑Cell Lymphoma

Xi Chen
Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, F-75006 Paris, France, Université Paris Cité, Paris 6e Arrondissement, France
76
1.00 pm (GMT+1)

NMR structure calculation with ARIA: recent and future developments

Nathalie Duclert-Savatier
Institut Pasteur, Université Paris Cité, CNRS UMR3528, Structural Bioinformatics Unit, Paris, France
78
1.00 pm (GMT+1)

Amyloid fibrils seen by 19F detected MAS NMR spectroscopy at fast MAS regime

Alons Lends
Latvian institute of organic synthesis, Riga, Latvia Institut de Chimie et de Biologie des Membranes et des Nanoobjets, Institut Européen de Chimie et Biologie, CNRS UMR 5248, Université de Bordeaux, Pessac, France
80
1.00 pm (GMT+1)

Regulation of the DNA-damage response by phosphorylation clusters in the p53 signaling network

Yingyue Luo
CNRS-I2bc, Bures Sur Yvette, France Univ. Paris-Saclay, France
82
1.00 pm (GMT+1)

In Situ Study of Poly (ADP-ribosylation) by Solid State NMR

Adrian Murgoci
Yusuf Hamied Department of Chemistry, Duer group, University of Cambridge, Cambridge, United Kingdom
84
1.00 pm (GMT+1)

Structure and assembly of PulL and PulM, two components of the Klebsiella oxytoca type II secretion system

Régine Dazzoni
Université Paris Cité, CNRS UMR3528, Structural Bioinformatics Unit, F-75015, Institut Pasteur, Paris, France
DYNAMIC AND DISORDERED SYSTEMS I
3.00 pm-4.15 pm (GMT+1)
Chair: Paul Robustelli, Dartmouth College, United States
18
3.00 pm (GMT+1)

NMR experiments and biomolecular simulations: A perfect match?

Kresten Lindorff-Larsen
Structural Biology and NMR Laboratory, Linderstrøm-Lang Centre for Protein Science, Univ. of Copenhagen, Denmark
19
3.30 pm (GMT+1)

Disordered, fuzzy and sticky: an NMR insight into the most versatile of respiratory syncytial virus proteins

Christina Sizun
Institut de Chimie des Substances Naturelles, CNRS, Université Paris Saclay, Gif-Sur-Yvette, France
20
4.00 pm (GMT+1)

Context matters - integrating structural disorder in structural biology

Birthe Kragelund
University of Copenhagen, Denmark
Coffee break
4.30 pm-5.15 pm (GMT+1)
RNA-PROTEIN COMPLEXES
5.15 pm-6.15 pm (GMT+1)
Chair: Muriel Delepierre, Institut Pasteur, CNRS, France
21
5.15 pm (GMT+1)

Structural Studies of the SARS-Cov2 Nucleoprotein-RNA Complex

Elisar Barbar
Oregon State University, United States
22
5.45 pm (GMT+1)

Dynamic regulation of protein-RNA and chaperone-client recognition

Michael Sattler
Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany Bavarian NMR Center, Department of Chemistry, Technical University of Munich, Garching, Germany
Wednesday, May 4, 2022
DYNAMIC AND DISORDERED SYSTEMS II
09.00 am-10.00 am (GMT+1)
Chair: Iñaki Guijarro, Institut Pasteur, France
23
09.00 am (GMT+1)

Aiming Higher - In Energy and Functional Understanding of Proteins

Dorothee Kern
Brandeis University, United States
24
09.30 am (GMT+1)

Just flexible linkers?

Roberta Pierattelli
Magnetic Resonance Center (CERM) and Department of Chemistry “Ugo Schiff”, CERM-University of Florence, Italy
Coffee break
10.00 am-10.45 am (GMT+1)
DRUG DISCOVERY AND DIAGNOSIS
10.45 am-12.15 pm (GMT+1)
Chair: Michael Nilges, Institut Pasteur, France
25
10.45 am (GMT+1)

Protein aggregation and interference with it for treatment and diagnosis studied by NMR  and beyond

Christian Griesinger
NMR-based Structural Biology, Max-Planck-Institute for Multidisciplinary Sciences, Göttingen, Germany
26
11.15 am (GMT+1)

How does the promiscuous nucleocapsid protein exert specific actions?

Fabio Almeida
University Federal Rio De Janeiro, Brazil
27
11.45 am (GMT+1)

NMR: An essential tool for discovery of HIF-2 inhibitors

Kevin Gardner
Director, Structural Biology Initiative, CUNY Advanced Science Research Center, United States
Closing remarks: On behalf of the organizing commmitte: Prof. Michael Nilges, Institut Pasteur, Paris
12.15 pm-12.30 pm (GMT+1)
CCPN Satellite workshop (only for registered attendees)
2.00 pm-6.00 pm (GMT+1)

 

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